Tech transfer revs up

NF1 inactivation revs up Ras in adult acute myelogenous leukemia.

Mutations in the Ras pathway are common in myeloid malignancies. NF1, a tumor suppressor and negative regulator of Ras, is inactivated in a subset of adult acute myelogenous leukemia (AML) cases. Loss of NF1 function sensitizes cells to inhibition of mammalian target of rapamycin (mTOR), a downstream effector of Ras activation, highlighting a potential therapeutic opportunity for some AML patie...

Technology Transfer and the Tech Broker

Statewide Heavy-Truck Crash Assessment tech transfer summary

This study used the most current statewide crash data to perform an indepth analysis of heavy-truck crashes in Iowa. This study also attempted to assess crash experience with respect to commercial driver’s license (CDL) licensure. In addition, this study used citation data from the Iowa Department of Transportation (DOT) Motor Vehicle Division and Iowa State Patrol to investigate the possible r...

Valuation of Early Stage High-tech Start-up Companies

Valuating start-ups, especially at early stages, is a challenge given the lack of historical data and many uncertain factors about the future. This article presents a methodology for the valuation of early stage start-ups that we have proven in practice. The risk linked to a start-up is expressed through an individual beta coefficient as important component of the discounting factor within a di...

Revs – a Robust Electronic Voting System

There are many protocols proposed for electronic voting, but only a few of them have prototypes implemented. Usually the prototypes are focused in the characteristics of the protocol and do not handle properly some real world issues, such as fault tolerance. This paper presents REVS, a robust electronic voting system designed for distributed and faulty environments, namely the Internet. The goa...